At Merida Biosciences, we are pioneering true precision medicines for antibody-driven diseases. We specifically target pathogenic antibodies and their cellular sources with bespoke Fc biotherapeutics engineered to selectively and completely eliminate the root causes of autoimmune and allergic diseases, and to achieve deep, durable responses while preserving essential immunity. We are looking for passionate individuals to join our mission to transform treatment paradigms across the spectrum of antibody-driven diseases.
We are looking for a self-motivated and intellectually curious Scientist/Senior Scientist to join our Biology/in vitro pharmacology group. The role will support pre-clinical efforts to characterize mechanism-of-action of therapeutics aimed at treating antibody-driven diseases. The ideal candidate is skilled lab-based in vitro biologist with a strong background in immunology and/or biologics drug discovery who can drive forward projects that serve multiple programs.
Responsibilities:
- Help drive multiple autoimmune programs to Development Candidate and IND
- Design and execute in vitro experiments to support preclinical drug discovery including disease modeling, and mechanism-of-action studies to deeply characterize our molecules.
- Collaborate with internal groups and lead study design for external CRO-based work, including biochemical analyses and in vivo studies
- Independently develop and execute quantitative assays (ELISAs, cell proliferation assays, etc.) to support molecule progression to DC and IND.
- Managing inventory and testing of patient samples that support multiple pre-clinical programs
- Interpret, summarize and present research findings in internal scientific meetings as part of our collaborative learning culture.
- Proactively review literature to bring newest scientific findings, ideas and technologies for discovery research
Requirements:
- PhD in with 0-3 years, a Masters with 6+ years, or a Bachelors with 8+ years of post-graduate academic or industry experience in relevant scientific fields such as immunology, cell/molecular biology or signal transduction
- Experience culturing and assaying human and mouse immune cells and cell lines using standard cell biology and molecular techniques (flow cytometry, ELISAs, Western Blot, PCR) is required.
- Experience culturing primary human B cells is a plus, as is experience designing viral vectors to express antigen receptors (particularly BCRs) and characterizing downstream signaling.
- Ability to work within a dynamic, matrixed environment.
- Excellent written and verbal communication skills, as well as strong organizational and problem-solving abilities.
Merida Biosciences is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
